Microcrystalline Cellulose 301
The core advantage of microcrystalline cellulose 301 lies in its superior performance resulting from its ultra-fine particle size. Over 90% of the particles can pass through a 200-mesh sieve, which not only ensures the mixing with active ingredients, effectively prevents component separation, and guarantees uniform content, but also endows the product with excellent suspension and rapid dissolution properties. In the direct compression process, its ultra-fine particles can significantly enhance the inter-particle binding force, and under appropriate pressure, high-hardness and rapidly disintegrating tablets can be prepared, especially suitable for orally disintegrating tablets, sublingual tablets, etc., which have high requirements for dissolution speed. At the same time, it supports up to 80% drug loading, providing an ideal solution for the development of innovative formulations.
Microcrystalline Cellulose 301 is a professional pharmaceutical excipient developed based on advanced ultra-micro pulverization technology, specifically designed for formulations with strict particle size requirements. This product is made from natural cellulose raw materials through a unique deep hydrolysis process and grading technology. It features a fine particle size distribution and excellent surface properties. As a representative of the fine specifications in the microcrystalline cellulose series, PH301 strictly follows the current pharmaceutical production management standards and fully complies with international mainstream pharmaceutical standards such as the Chinese Pharmacopoeia, the United States Pharmacopeia, and the European Pharmacopoeia. Its superior ultra-microscopic characteristics make it outstanding in innovative formulations that require rapid dissolution and high content uniformity. It is particularly suitable for the development of formulations with special requirements for taste and dissolution performance.
Superior dispersion and suspension properties
The core advantage of microcrystalline cellulose PH301 lies in its outstanding performance due to its ultra-fine particle size. The product's particle size distribution data shows that over 90% of the particles can pass through a 200-mesh sieve. This characteristic gives it a large specific surface area, enabling it to quickly wet and form a stable suspension when exposed to water. It exhibits excellent suspension performance in liquid media, effectively delaying particle sedimentation and having rapid dispersion properties, significantly enhancing the convenience and bioavailability of the formulation.
Content uniformity guarantee
Thanks to its ultra-fine particle size characteristic, PH301 can achieve molecular-level uniform mixing with active ingredients, effectively avoiding component separation during the production process. This feature makes it particularly suitable for the development of formulations for low-dose, high-activity drugs, ensuring the accuracy and consistency of each dose and providing a reliable guarantee for the production of high-quality formulations, effectively meeting the strict requirements for content uniformity in modern pharmaceutical industry.
Compression and molding performance
Despite its fine particle size, PH301 still maintains good compression properties. Its ultra-fine particles provide a larger specific surface area, significantly enhancing the binding force between particles, and can achieve the desired tablet hardness under appropriate pressure conditions. This characteristic makes it perform exceptionally well in direct tabletting processes, especially suitable for preparing tablets with high hardness and rapid disintegration, while maintaining good friability indicators.
Widely compatible product properties
The product has good compatibility with the vast majority of active ingredients and pharmaceutical excipients, maintaining stable performance in different formulation systems. Its chemical inertness ensures no interaction with drug components, providing multiple guarantees for the quality and safety of the formulation. At the same time, the product can maintain stable physical and chemical properties under different temperature and humidity conditions.
