Microcrystalline Cellulose 105
Microcrystalline cellulose 105, with its fine particle size and extremely large specific surface area, boasts unparalleled ultimate compressibility and adhesion. It can easily produce tablets with extremely high hardness, perfectly solving the problem of uniformity in the content of highly active and low-dose drugs. At the same time, 105 is an ideal choice for preparing micro-powder cores with excellent mechanical strength and smooth surface, providing a solid and reliable foundation for your multi-layer tablets, oral disintegrating tablets and other high-end preparations.
Microcrystalline cellulose 105 - Exceptional compressibility, specially designed for high-hardness tablets and micro-powder cores.
Microcrystalline cellulose 105 is our newly launched fine-particle size oral-grade excipient. It achieves unparalleled specific surface area and dense bonding ability through a smaller particle size distribution, providing an ideal solution for high-end formulations with extreme requirements for tablet hardness, content uniformity, or core strength.
Core advantages:
Ultra-high compressibility, achieving high hardness tablets: Microcrystalline cellulose 105 has a smaller particle size and a larger specific surface area, enabling particles to form a more compact bond during the tabletting process. It is the preferred choice for preparing high-hardness, low-dose tablets or handling APIs with poor compressibility.
Better content uniformity: Fine powder can more evenly encapsulate the active ingredient, effectively reducing the separation phenomenon after mixing, significantly improving the uniformity of low-dose drug content, and ensuring precise drug delivery in each tablet.
Strong adhesion, constructing perfect micro pellets: When preparing the micro pellet matrix by the extrusion-molding method, 105 can provide strong cohesion and molding properties, creating high mechanical strength and smooth, round blank cores with excellent quality, laying a solid foundation for subsequent drug loading and coating processes.
Multifunctional integration, wide application: It also possesses dilution, adhesion and disintegration functions, and is not only suitable for conventional oral tablets, but also ideal excipients for special dosage forms such as oral disintegrating tablets, lozenges and multi-layer tablets.
Main applications:
Tablets with strict requirements for hardness and content uniformity (such as low-dose drugs)
Blank core for micro pellet matrix prepared by extrusion-molding
Special dosage forms such as oral disintegrating tablets, lozenges, etc.
Wet granulation process (as an adsorbent and to improve compressibility)
